Authors

    Language

    English

    Publication Date

    2-1-2023

    Journal

    Reproduction

    DOI

    10.1530/REP-22-0250

    PMID

    36318634

    PMCID

    PMC9827618

    PubMedCentral® Posted Date

    2-1-2023

    PubMedCentral® Full Text Version

    Author MSS

    Abstract

    IN BRIEF: In vivo imaging of gametes and embryos in the oviduct enables new studies of the native processes that lead to fertilization and pregnancy. This review article discusses recent advancements in the in vivo imaging methods and insights which contribute to understanding the oviductal function.

    ABSTRACT: Understanding the physiological dynamics of gametes and embryos in the fallopian tube (oviduct) has significant implications for managing reproductive disorders and improving assisted reproductive technologies. Recent advancements in imaging of the mouse oviduct in vivo uncovered fascinating dynamics of gametes and embryos in their native states. These new imaging approaches and observations are bringing exciting momentum to uncover the otherwise-hidden processes orchestrating fertilization and pregnancy. For mechanistic investigations, in vivo imaging in genetic mouse models enables dynamic phenotyping of gene functions in the reproductive process. Here, we review these imaging methods, discuss insights recently revealed by in vivo imaging, and comment on emerging directions, aiming to stimulate new in vivo studies of reproductive dynamics.

    Keywords

    Pregnancy, Humans, Female, Animals, Mice, Fallopian Tubes, Oviducts, Germ Cells, Reproduction, Diagnostic Imaging, Oviduct, gamete, preimplantation embryo, in vivo imaging, mouse

    Published Open-Access

    yes

    Share

    COinS
     
     

    To view the content in your browser, please download Adobe Reader or, alternately,
    you may Download the file to your hard drive.

    NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.