Language
English
Publication Date
10-15-2026
Journal
Journal of Clinical Investigation
DOI
10.1172/JCI204909
PMID
42640719
PMCID
PMC13668626
PubMedCentral® Posted Date
8-25-2026
PubMedCentral® Full Text Version
Post-print
Abstract
Chemotherapy drugs that fight childhood cancer can age heart cells prematurely. We found this "cellular aging" throughout the hearts of children with treatment-related heart failure.
Keywords
Humans, Anthracyclines, Cellular Senescence, Cardiomyopathies, Transcriptome, Child, Heart Failure, Cardiology, Oncology, Heart failure
Published Open-Access
yes
Recommended Citation
Turaga, Diwakar; Tsai, Chang-Ru; Morikawa, Yuka; et al., "Single-Nuclei Transcriptomics Reveals Cellular Senescence in Pediatric Anthracycline-Induced Cardiomyopathy" (2026). Faculty, Staff and Students Publications. 8586.
https://digitalcommons.library.tmc.edu/baylor_docs/8586