Publication Date
9-1-2023
Journal
The Texas Heart Journal
DOI
10.14503/THIJ-23-8148
PMID
37872693
Publication Date(s)
September 2023
Language
English
PMCID
PMC10658142
PubMedCentral® Posted Date
10-23-2023
PubMedCentral® Full Text Version
Post-Print
Published Open-Access
yes
Keywords
Humans, Polycythemia, Polycythemia Vera, ST Elevation Myocardial Infarction, Myocardial Infarction, Thrombosis, Janus Kinase 2
Copyright
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Abstract
Thrombotic and bleeding complications are major causes of morbidity and mortality in patients with polycythemia vera, who predominantly present with an alteration in the JAK2 gene. Because of their hypercoagulable state and risk of hemorrhage, patients with polycythemia vera who present with an acute myocardial infarction pose a challenge to physicians. This case report describes the presentation and treatment of a Hispanic patient with JAK2 V617F-negative primary polycythemia who developed cardiac arrest and ST-segment elevation myocardial infarction owing to complete occlusion of the left anterior descending artery as well as bleeding complications and postmyocardial pericarditis.