Publication Date
2-1-2016
Journal
The Texas Heart Journal
DOI
10.14503/THIJ-14-4407
PMID
27047280
Publication Date(s)
February 2016
Language
English
PMCID
PMC4810578
PubMedCentral® Posted Date
2-1-2016
PubMedCentral® Full Text Version
Post-Print
Published Open-Access
yes
Keywords
Adult, Aged, Aged, 80 and over, Animals, Bioprosthesis, Echocardiography, Female, Follow-Up Studies, Heart Valve Diseases, Hemodynamics, Humans, Incidence, Italy, Male, Middle Aged, Mitral Valve, Postoperative Complications, Prognosis, Prosthesis Design, Retrospective Studies, Survival Rate, Swine, Time Factors
Copyright
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Abstract
We reviewed the cases of 100 patients (mean age, 73 ± 10 yr; 64 men) who had mitral valve replacement with a Medtronic Mosaic porcine bioprosthesis from 1995 through 2011. The mean New York Heart Association (NYHA) class was 3 ± 0.7, and 52 patients were in atrial fibrillation. Prosthetic sizes were chiefly 27 mm (50 patients) and 29 mm (40 patients). Follow-up ended in December 2012 and is 97% complete, with a cumulative duration of 611 patient-years (mean duration, 6 ± 4.6 yr; maximum, 17.7 yr). The early mortality rate was 10% (6% in elective patients); late deaths occurred in 31 patients (5 valve-related). Actuarial survival rates at 5, 10, and 15 years were 74% ± 5%, 50% ± 6%, and 37% ± 8%. The mean NYHA class in survivors was 1.4 ± 0.6 (P