Language

English

Publication Date

2-1-2016

Journal

The Texas Heart Institute Journal

DOI

10.14503/THIJ-14-4407

PMID

27047280

PMCID

PMC4810578

PubMedCentral® Posted Date

2-1-2016

PubMedCentral® Full Text Version

Post-Print

Abstract

We reviewed the cases of 100 patients (mean age, 73 ± 10 yr; 64 men) who had mitral valve replacement with a Medtronic Mosaic porcine bioprosthesis from 1995 through 2011. The mean New York Heart Association (NYHA) class was 3 ± 0.7, and 52 patients were in atrial fibrillation. Prosthetic sizes were chiefly 27 mm (50 patients) and 29 mm (40 patients). Follow-up ended in December 2012 and is 97% complete, with a cumulative duration of 611 patient-years (mean duration, 6 ± 4.6 yr; maximum, 17.7 yr). The early mortality rate was 10% (6% in elective patients); late deaths occurred in 31 patients (5 valve-related). Actuarial survival rates at 5, 10, and 15 years were 74% ± 5%, 50% ± 6%, and 37% ± 8%. The mean NYHA class in survivors was 1.4 ± 0.6 (P

Keywords

Adult, Aged, Aged, 80 and over, Animals, Bioprosthesis, Echocardiography, Female, Follow-Up Studies, Heart Valve Diseases, Hemodynamics, Humans, Incidence, Italy, Male, Middle Aged, Mitral Valve, Postoperative Complications, Prognosis, Prosthesis Design, Retrospective Studies, Survival Rate, Swine, Time Factors

Published Open-Access

yes

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