Student and Faculty Publications
Publication Date
12-1-2022
Journal
Annals of Dermatology
Abstract
BACKGROUND: Avoiding causative allergens is important for controlling the clinical course of allergic diseases. Allergen sensitization is influenced by many factors including the environment and lifestyle. The socioeconomic development, climate, and lifestyle changes have increased the prevalence of allergic diseases worldwide. However, there is little information about changes in the trend of the common allergens over time.
OBJECTIVE: This study was aimed at identifying the trends of the common allergens in Korea over a 10-year period based on the results of the multiple allergosorbent test chemiluminescent assay (MAST-CLA).
METHODS: We retrospectively reviewed the medical records of 5,760 patients aged ≥18 years who visited the Dermatology Department at a tertiary hospital over a period of 10 years. The serum total immunoglobulin (Ig) E and specific IgE levels to 41 allergens were determined using MAST-CLA, along with the clinical diagnosis, duration of illness, white blood cell count and eosinophil percentage.
RESULTS:
CONCLUSION: The common allergens have changed over time. Based on the findings of this study, physicians and patients should consider changing their strategies for disease prevention and management.
Keywords
Allergens, Allergy, Atopic dermatitis, Immunoglobulin E, Multiple allergosorbent test chemiluminescent assay, Time trend
Included in
Allergy and Immunology Commons, Bioinformatics Commons, Biomedical Informatics Commons, Dermatology Commons, Medical Sciences Commons, Race and Ethnicity Commons, Skin and Connective Tissue Diseases Commons
Comments
Supplementary Materials
PMID: 36478425