Publication Date
5-1-2021
Journal
American Journal of Physiology-Lung Cellular and Molecular Physiology
Abstract
The mechanisms responsible for driving endogenous airway hyperresponsiveness (AHR) in the form of exercise-induced bronchoconstriction (EIB) are not fully understood. We examined alterations in airway phospholipid hydrolysis, surfactant degradation, and lipid mediator release in relation to AHR severity and changes induced by exercise challenge. Paired induced sputum (
Keywords
Adolescent, Adult, Asthma, Bronchoconstriction, Eicosanoids, Exercise, Female, Group X Phospholipases A2, Humans, Hydrolysis, Male, Osmotic Pressure, Phospholipids, Respiratory Hypersensitivity, Sputum, Surface-Active Agents, Young Adult