Publication Date
5-15-2023
Journal
Nature Communications
Abstract
Cardiolipin is a hallmark phospholipid of mitochondrial membranes. Despite established significance of cardiolipin in supporting respiratory supercomplex organization, a mechanistic understanding of this lipid-protein interaction is still lacking. To address the essential role of cardiolipin in supercomplex organization, we report cryo-EM structures of a wild type supercomplex (IV
Keywords
Saccharomyces cerevisiae, Cardiolipins, Phosphatidylglycerols, Phospholipids, Saccharomyces cerevisiae Proteins