A Case Report Navigating Cvid and Sarcoidosis Overlaps in Pediatric Nephritis

Authors

Amanda Salih
Amanda Brown
Amanda Grimes
Sana Hasan
Manuel Silva-Carmona
Leyat Tal
Joud Hajjar

Publication Date

1-1-2024

Journal

Frontiers in Pediatrics

DOI

10.3389/fped.2024.1417724

PMID

39359743

PMCID

PMC11445013

PubMedCentral® Posted Date

9-18-2024

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes

Keywords

CVID, granulomatous disease, hypogammaglobulinemia, sarcoidosis, GLILD, granulomatous lymphocytic interstitial lung disease

Abstract

Common variable immunodeficiency (CVID) can be complicated by granulomatous disease, often granulomatous lymphocytic interstitial lung disease (GLILD). Granulomatous interstitial nephritis represents an atypical presentation in pediatrics. Our patient is a previously healthy 13-year-old white male with a recent diagnosis of CVID. He presented with a rash and laboratory findings included pancytopenia (white blood cells 2.6 cells × 10

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