Publication Date

11-2-2022

Journal

The EMBO Journal

DOI

10.15252/embj.2022112435

PMID

36120982

PMCID

PMC9627662

PubMedCentral® Posted Date

9-19-2022

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes

Keywords

Animals, Methylation, Stem Cells, Planarians, Cell Differentiation, RNA, Messenger, RNA Interference

Abstract

The contribution of RNA modifications to whole-body regeneration remains unclear. In this issue, Dagan et al (2022) show that m6a mRNA pathway components are critically required for stem cell differentiation, survival, and tissue renewal in the planarian Schmidtea mediterranea.

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