Publication Date

9-15-2023

Journal

iScience

DOI

10.1016/j.isci.2023.107596

PMID

37664586

PMCID

PMC10470378

PubMedCentral® Posted Date

8-9-2023

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes

Keywords

Cell biology, Immunology, Microbiology, Stem cells research, Transcriptomics

Abstract

Recent studies suggest that infection reprograms hematopoietic stem and progenitor cells (HSPCs) to enhance innate immune responses upon secondary infectious challenge, a process called "trained immunity." However, the specificity and cell types responsible for this response remain poorly defined. We established a model of trained immunity in mice in response to

fx1.jpg (637 kB)
Graphical Abstract

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.