Language
English
Publication Date
9-15-2023
Journal
iScience
DOI
10.1016/j.isci.2023.107596
PMID
37664586
PMCID
PMC10470378
PubMedCentral® Posted Date
8-9-2023
PubMedCentral® Full Text Version
Post-print
Abstract
Recent studies suggest that infection reprograms hematopoietic stem and progenitor cells (HSPCs) to enhance innate immune responses upon secondary infectious challenge, a process called "trained immunity." However, the specificity and cell types responsible for this response remain poorly defined. We established a model of trained immunity in mice in response to
Keywords
Cell biology, Immunology, Microbiology, Stem cells research, Transcriptomics
Published Open-Access
yes
Recommended Citation
Kain, Bailee N; Tran, Brandon T; Luna, Pamela N; et al., "Hematopoietic Stem and Progenitor Cells Confer Cross-Protective Trained Immunity in Mouse Models" (2023). Faculty and Staff Publications. 1907.
https://digitalcommons.library.tmc.edu/baylor_docs/1907
Graphical Abstract
Included in
Biological Phenomena, Cell Phenomena, and Immunity Commons, Life Sciences Commons, Medical Cell Biology Commons, Medical Microbiology Commons, Medical Molecular Biology Commons, Medical Specialties Commons