Publication Date
2-1-2023
Journal
Cellular Reprogramming
DOI
10.1089/cell.2022.0153
PMID
36594927
PMCID
PMC9963505
PubMedCentral® Posted Date
2-14-2023
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Keywords
Animals, Mice, Longevity, Cellular Reprogramming, Epigenesis, Genetic, Rejuvenation, Aging
Abstract
Short-term expression of Yamanaka factors early in life promotes epigenetic reprogramming and an increased healthy lifespan in a mouse model of accelerated aging.
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