Publication Date
10-7-2024
Journal
Epilepsy Currents
DOI
10.1177/15357597241281838
PMID
39539402
PMCID
PMC11556333
PubMedCentral® Posted Date
10-7-2024
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Keywords
antiseizure medications, precision medicine, status epilepticus, access to seizure medications, pharmacology, epilepsies, global
Abstract
Since bromides were first used in 1857 to treat epilepsy, numerous antiseizure medications (ASM) have been developed. Many of these are available for the treatment of epilepsy and status epilepticus today. With so many ASM available, questions arise as to whether all of these medications are needed and when should they be used. As precision medicine begins to play a larger role in determining targeted treatments for specific types of epilepsy, a complete understanding of various medications is needed. Additionally, access to several of these medications can be limited in the United States and are especially limited globally. All these factors can make proper selection of ASM challenging and difficult for clinicians. This review highlights important aspects of older and newer medications, developments in precision medicine for epilepsy, increasing understanding of effective treatments for status epileptics, and a global perspective on ASM availability.
Included in
Medical Sciences Commons, Mental and Social Health Commons, Nervous System Diseases Commons, Neurology Commons