Publication Date
4-17-2024
Journal
The Journal of Neuroscience
DOI
10.1523/JNEUROSCI.1433-23.2024
PMID
38423760
PMCID
PMC11026348
PubMedCentral® Posted Date
2-29-2024
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Keywords
Animals, Photoreceptor Cells, Retina, Caudata, HCN channels, I h, junctional resistance, linear cable equation, photoreceptor coupling, rod–rod coupled network, space constant, time-to-peak, ZD7288
Abstract
Photoreceptors are electrically coupled to one another, and the spatiotemporal properties of electrical synapses in a two-dimensional retinal network are still not well studied, because of the limitation of the single electrode or pair recording techniques which do not allow simultaneously measuring responses of multiple photoreceptors at various locations in the retina. A multiple electrode recording system is needed. In this study, we investigate the network properties of the two-dimensional rod coupled array of the salamander retina (both sexes were used) by using the newly available multiple patch electrode system that allows simultaneous recordings from up to eight cells and to determine the electrical connectivity among multiple rods. We found direct evidence that voltage signal spread in the rod-rod coupling network in the absence of