Publication Date
1-1-2022
Journal
Frontiers in Ophthalmology
DOI
10.3389/fopht.2022.896680
PMID
38983539
PMCID
PMC11182282
PubMedCentral® Posted Date
6-28-2022
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Keywords
translaminar pressure difference, translaminar pressure gradient, cerebrospinal fluid, glaucoma, lamina cribrosa
Abstract
There has been significant interest and progress in the understanding of cerebrospinal fluid pressure and its relationship to glaucoma and other ophthalmic diseases. However, just as every physiologic fluid pressure fluctuates, cerebrospinal fluid pressure (CSFP) is similarly dynamic. Coupling this with the difficulty in measuring the pressure, there are many obstacles in furthering this field of study. This review highlights some of the difficulties in CSFP research, including fluid compartmentalization, estimation equations, and pressure fluctuation. Keeping these limitations in mind will hopefully improve the quality and context of this burgeoning field.