Publication Date
3-17-2023
Journal
International Journal of Molecular Sciences
DOI
10.3390/ijms24065740
PMID
36982810
PMCID
PMC10053331
PubMedCentral® Posted Date
3-17-2023
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Keywords
Animals, Mice, Female, Mice, Inbred C57BL, Conjunctival Diseases, Conjunctiva, Cautery, Inflammation, Lasers
Abstract
Conjunctivochalasis is a degenerative condition of the conjunctiva that disrupts tear distribution and causes irritation. Thermoreduction of the redundant conjunctiva is required if symptoms are not relieved with medical therapy. Near-infrared laser treatment is a more controlled method to shrink the conjunctiva than thermocautery. This study compared tissue shrinkage, histology, and postoperative inflammation in thermoconjunctivoplasty performed on the mouse conjunctiva using either thermocautery or pulsed 1460 nm near-infrared laser irradiation. Three sets of experiments were performed on female C57BL/6J mice (