Publication Date
8-25-2023
Journal
International Journal of Molecular Sciences
DOI
10.3390/ijms241713221
PMID
37686027
PMCID
: PMC10487846
PubMedCentral® Posted Date
8-26-2023
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Keywords
Insecticides, Bandages, Biological Transport, Crystallography, X-Ray, Protein Folding, Toxins, Biological, TcA, toxin translocase, Cryo-EM, X-ray crystallography
Abstract
The Toxin Complex (Tc) superfamily consists of toxin translocases that contribute to the targeting, delivery, and cytotoxicity of certain pathogenic Gram-negative bacteria. Membrane receptor targeting is driven by the A-subunit (TcA), which comprises IgG-like receptor binding domains (RBDs) at the surface. To better understand XptA2, an insect specific TcA secreted by the symbiont
Included in
Biochemistry, Biophysics, and Structural Biology Commons, Biology Commons, Medical Specialties Commons, Medical Toxicology Commons
Comments
Associated Data