Language
English
Publication Date
8-25-2023
Journal
International Journal of Molecular Sciences
DOI
10.3390/ijms241713221
PMID
37686027
PMCID
: PMC10487846
PubMedCentral® Posted Date
8-26-2023
PubMedCentral® Full Text Version
Post-print
Abstract
The Toxin Complex (Tc) superfamily consists of toxin translocases that contribute to the targeting, delivery, and cytotoxicity of certain pathogenic Gram-negative bacteria. Membrane receptor targeting is driven by the A-subunit (TcA), which comprises IgG-like receptor binding domains (RBDs) at the surface. To better understand XptA2, an insect specific TcA secreted by the symbiont
Keywords
Insecticides, Bandages, Biological Transport, Crystallography, X-Ray, Protein Folding, Toxins, Biological, TcA, toxin translocase, Cryo-EM, X-ray crystallography
Published Open-Access
yes
Recommended Citation
Martin, Cole L; Chester, David W; Radka, Christopher D; et al., "Structures of the Insecticidal Toxin Complex Subunit XptA2 Highlight Roles for Flexible Domains" (2023). Faculty and Staff Publications. 350.
https://digitalcommons.library.tmc.edu/baylor_docs/350
Included in
Biochemistry, Biophysics, and Structural Biology Commons, Biology Commons, Medical Specialties Commons, Medical Toxicology Commons