Language
English
Publication Date
1-1-2025
Journal
Baylor University Medical Center Proceedings
DOI
10.1080/08998280.2025.2458993
PMID
39990001
PMCID
PMC11844923
PubMedCentral® Posted Date
2-5-2025
PubMedCentral® Full Text Version
Post-print
Abstract
This study investigated erythema ab igne (EAI) and comorbid skin cancers. Each EAI case, searched by ICD-10-CM code L59.0 in the All of Us database, was compared to four controls, matched by sex at birth, age, and self-identified race/ethnicity. Demographics and skin cancer comorbidities were assessed with odds ratios (ORs) and 95% confidence intervals (CIs) using Wald’s method. EAI was most prevalent between 60 and 70 years of age. A female-to-male ratio of 1:1 was observed between ages 40 and 50. EAI patients had a statistically significant increased risk of basal cell carcinoma (OR, 10.67; 95% CI, 2.76–41.30; P < 0.001), squamous cell carcinoma (OR, 27.84; 95% CI, 1.42–545.59; P = 0.03), and melanoma (OR, 8.00; 95% CI, 1.43–44.60; P = 0.02). Additional tumors were analyzed, but insufficient case/control data was obtained from the database. In conclusion, EAI is positively correlated with skin cancers. Awareness and prevention of EAI is warranted.
Keywords
Basal cell carcinoma, case-control analysis, erythema ab igne, melanoma, skin cancer
Published Open-Access
yes
Recommended Citation
Verma, Kritin K; Dhavala, Maitreyi; Vo, Jalyn; et al., "From Toasted Skin to Tumors: A Retrospective Nationwide Case-Control Analysis Investigating the Link Between Erythema Ab Igne and Various Skin Cancers" (2025). Faculty and Staff Publications. 3879.
https://digitalcommons.library.tmc.edu/baylor_docs/3879