Language
English
Publication Date
1-29-2023
Journal
Journal of Clinical Medicine
DOI
10.3390/jcm12031059
PMID
36769707
PMCID
PMC9917529
PubMedCentral® Posted Date
1-29-2023
PubMedCentral® Full Text Version
Post-print
Abstract
COVID-19 in pregnant women increases the risk of adverse pregnancy outcomes, including preeclampsia. This meta-analysis aimed to examine the effect of SARS-CoV-2 infection on sFlt-1/PIGF ratio during pregnancy. The study was designed as a systematic review and meta-analysis. PubMed, Web of Science, Embase and Cochrane Library were searched for relevant studies reporting the sFlt-1/PlGF ratio in pregnant women with COVID-19. Results were compared using meta-analysis by the Mantel-Haenszel method. A total of 7 studies were included in the analysis. sFlt-1/PlGF ratios between COVID-19 positive vs. negative women were 45.8 ± 50.3 vs. 37.4 ± 22.5, respectively (SMD = 1.76; 95% CI: 0.43 to 3.09;
Keywords
COVID-19, SARS-CoV-2, sFlt-1/PlGF ratio, RAS, placental dysfunction, pregnancy
Published Open-Access
yes
Recommended Citation
Kosinska-Kaczynska, Katarzyna; Malicka, Ewa; Szymusik, Iwona; et al., "The sFlt-1/PlGF Ratio in Pregnant Patients Affected by COVID-19" (2023). Faculty and Staff Publications. 3916.
https://digitalcommons.library.tmc.edu/baylor_docs/3916
Included in
Clinical Epidemiology Commons, COVID-19 Commons, Medical Sciences Commons, Medical Specialties Commons