Regrowing the Heart, One Tree at a Time

Authors

Jeffrey D Steimle
James F Martin

Language

English

Publication Date

1-5-2023

Journal

Cell Stem Cell

DOI

10.1016/j.stem.2022.12.004

PMID

36608673

Abstract

While many animals can completely repair injured tissues, the mammalian heart possesses limited regenerative capabilities. Yan and Cigliola et al. show that AAV-mediated, zebrafish-derived tissue regeneration enhancer elements (TREEs) can direct pro-regenerative gene expression in injured cardiac tissue of mice and pigs that turn off following repair.

Keywords

Animals, Swine, Zebrafish, Heart, Cell Proliferation, Mammals, Wound Healing, Myocytes, Cardiac

Published Open-Access

yes

Recommended Citation

Jeffrey D Steimle and James F Martin, "Regrowing the Heart, One Tree at a Time" (2023). Faculty and Staff Publications. 3992.
https://digitalcommons.library.tmc.edu/baylor_docs/3992