Language

English

Publication Date

7-10-2025

Journal

Journal of Clinical Medicine

DOI

10.3390/jcm14144906

PMID

40725597

PMCID

PMC12295626

PubMedCentral® Posted Date

7-10-2025

PubMedCentral® Full Text Version

Post-print

Abstract

Aortic stenosis is the most prevalent valvular disease globally. Transcatheter aortic valve replacement (TAVR) has become a well-established treatment for aortic stenosis, offering outcomes comparable to surgical aortic valve replacement (SAVR). Its use has expanded to include younger, lower-risk patients and those with more complex anatomies. Recent advancements in TAVR include the increased adoption of transfemoral access, prosthesis designs optimized for challenging anatomies, enhanced delivery systems with repositioning capabilities, and outer skirts to minimize paravalvular leaks. Despite these innovations, several challenges remain. This review highlights recent updates in transcatheter heart valve (THV) systems, leaflet modification devices, and the current limitations of TAVR.

Keywords

TAVR, THV design, leaflet modification

Published Open-Access

yes

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