Language
English
Publication Date
12-15-2024
Journal
Journal of Clinical Medicine
DOI
10.3390/jcm13247637
PMID
39768560
PMCID
PMC11728314
PubMedCentral® Posted Date
12-15-2024
Abstract
Advances in imaging, pharmacological, and procedural technologies have rapidly expanded the care of pulmonary embolism. Earlier, more accurate identification and quantification has enhanced risk stratification across the spectrum of the disease process, with a number of clinical tools available to prognosticate outcomes and guide treatment. Direct oral anticoagulants have enabled a consistent and more convenient long-term therapeutic option, with a greater shift toward outpatient treatment for a select group of low-risk patients. The array of catheter-directed therapies now available has contributed to a more versatile and nuanced armamentarium of treatment options, including ultrasound-facilitated thrombolysis and mechanical thrombectomy. Research into supportive care for pulmonary embolism have explored the optimal use of vasopressors and volume resuscitation, as well as utilization of various devices, including right ventricular mechanical support and extracorporeal membrane oxygenation. Even in the realm of surgery, outcomes have steadily improved in experienced centers. This rapid expansion in diagnostic and therapeutic data has necessitated implementation of pulmonary embolism response teams to better interpret the available evidence, manage the utilization of advanced therapies, and coordinate multidisciplinary care. We provide a narrative review of the risk stratification and management of pulmonary embolism, with a focus on structuralizing the multidisciplinary approach and organizing the literature on new and emerging therapies.
Keywords
PE, pulmonary embolism, VTE
Published Open-Access
yes
Recommended Citation
Benavente, Kevin; Fujiuchi, Bradley; Virk, Hafeez Ul Hassan; et al., "A Practical Clinical Approach to Navigate Pulmonary Embolism Management: A Primer and Narrative Review of the Evolving Landscape" (2024). Faculty and Staff Publications. 4205.
https://digitalcommons.library.tmc.edu/baylor_docs/4205