Language

English

Publication Date

12-1-2024

Journal

JACC: Advances

DOI

10.1016/j.jacadv.2024.101402

PMID

39735779

PMCID

PMC11681797

PubMedCentral® Posted Date

12-26-2024

PubMedCentral® Full Text Version

Author MSS

Abstract

Acute decompensated valvular disease encompasses a group of complex and challenging conditions, which are often the primary reason for admission to the cardiac intensive care unit and can also complicate the management of other primary cardiac disorders. Critically ill patients with valvular disease also present unique diagnostic and management challenges. Historically, medical and percutaneous interventional therapies have been limited and surgery was the only definitive treatment; however, surgical risk can at times be prohibitive. High-quality evidence to direct management of acute valvular disorders in this population is lacking and societal guidelines largely do not address treatment options for critically ill patients with decompensated valvular disease. In this review, we discuss the clinical presentation and epidemiology of commonly encountered valvular diseases in the modern cardiac intensive care unit, highlight key pathophysiology, detail gaps in evidence, describe the pivotal role of multidisciplinary Heart Teams, and provide guidance for management.

Keywords

cardiac intensive care unit, cardiogenic shock, valvular disease

Published Open-Access

yes

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