Language
English
Publication Date
9-1-2025
DOI
10.1016/j.jacadv.2025.102078
PMID
40834806
PMCID
PMC12395060
PubMedCentral® Posted Date
8-19-2025
PubMedCentral® Full Text Version
Post-print
Abstract
Background: Characteristics and outcomes associated with cardiogenic shock (CS) with acute myocardial infarction (AMI) in older patients have not been well characterized.
Objectives: The purpose of this study was to investigate characteristics and outcomes of older patients admitted with CS with AMI.
Methods: We used the National Inpatient Sample database to evaluate clinical characteristics of hospitalizations, clinical outcomes, and health care utilization of hospitalizations of older patients ≥80 years with CS and AMI from 2003 to 2021. We also compared data from older patients with a reference relatively younger patient population (18-79 years).
Results: During the study period, 207,333 hospitalizations of older patients ≥80 years and 675,491 hospitalizations of patients 18 to 79 years were identified. Between the first 4 years of the study period (2003-2006) and the final 4-year interval of the study period (2016-2019), there was an increase in the number of hospitalizations of older patients with AMI and CS (39,220-51,640). On adjusted analysis, there were increases in the percentage of older patients undergoing treatment with percutaneous coronary intervention (19.2% to 34.1%; P < 0.001) and encounters for palliative care (2.0% to 32.4%; P < 0.001) alongside a decline in in-hospital mortality (61.4% to 49.0%; P < 0.001) over the study period. Compared to patients 18 to 79 years of age, those aged ≥80 years had greater in-hospital mortality (51.8% vs 33.0%; P < 0.001).
Conclusions: From 2003 to 2021, for older patients with CS and AMI, hospitalizations increased, and mortality decreased.
Keywords
acute myocardial infarction, cardiogenic shock, older patients
Published Open-Access
yes
Recommended Citation
Mansoor, Taha; Jabbar, Ali Bin Abdul; Ismayl, Mahmoud; et al., "Cardiogenic Shock With Acute Myocardial Infarction Among Older Adults in the United States" (2025). Faculty and Staff Publications. 4287.
https://digitalcommons.library.tmc.edu/baylor_docs/4287
Graphical Abstract