Language
English
Publication Date
5-8-2023
Journal
Microorganisms
DOI
10.3390/microorganisms11051239
PMID
37317213
PMCID
PMC10220574
PubMedCentral® Posted Date
5-8-2023
PubMedCentral® Full Text Version
Post-print
Abstract
Helicobacter pylori antimicrobial resistance is a critical public health issue. Typically, antimicrobial resistance epidemiology reports include only the antimicrobial susceptibility test results for H. pylori. However, this phenotypic approach is less capable of answering queries related to resistance mechanisms and specific mutations found in particular global regions. Whole genome sequencing can help address these two questions while still offering quality control and is routinely validated against AST standards. A comprehensive understanding of the mechanisms of resistance should improve H. pylori eradication efforts and prevent gastric cancer.
Keywords
Helicobacter pylori, whole genome sequencing, antimicrobial resistance, infectious disease
Published Open-Access
yes
Recommended Citation
Kartika Afrida Fauzia, Ricky Indra Alfaray, and Yoshio Yamaoka, "Advantages of Whole Genome Sequencing in Mitigating the Helicobacter pylori Antimicrobial Resistance Problem" (2023). Faculty and Staff Publications. 4444.
https://digitalcommons.library.tmc.edu/baylor_docs/4444