Language
English
Publication Date
12-1-2024
DOI
10.1080/21691401.2024.2338127
PMID
38590145
PubMedCentral® Posted Date
12-1-2024
Abstract
The cytological behaviour and functional dynamics (adhesion, spreading, synthesis of proteins) of fibroblasts when interacting with biomedical surfaces are intricately influenced by the inherent nature of surface (nanocrystalline or microcrystalline), where the nanocrystalline (NC) surface is preferred in relation to the microcrystalline (MC) surface. This preference is a direct consequence of the distinct differences in physical and chemical characteristics between NC and MC surfaces, which include crystal boundary bio-physical attributes, electron work function, surface energy, and charge carrier density. The observed variances in cytological behaviour at the interfaces of NC and MC bio-surfaces can be attributed to these fundamental differences, particularly accounting for the percentage and nature of crystal boundaries. Recognising and understanding these physical and chemical characteristics establish the groundwork for formulating precise guidelines crucial in the development of the forthcoming generation of biomedical devices.
Keywords
Surface Properties, Fibroblasts, Biomedical stainless steel, biological functionality, crystal boundary attributes, nanocrystalline
Published Open-Access
yes
Recommended Citation
R D K Misra and Aladin M Boriek, "Exploring Fibroblast Interactions on Nanocrystalline Surfaces in Physiological Environments Through a Phenomenological Lens" (2024). Faculty and Staff Publications. 4770.
https://digitalcommons.library.tmc.edu/baylor_docs/4770
Included in
Critical Care Commons, Health Services Research Commons, Medical Sciences Commons, Pulmonology Commons, Sleep Medicine Commons