Language
English
Publication Date
2-1-2024
Journal
Cureus
DOI
10.7759/cureus.54127
PMID
38487135
PMCID
PMC10939161
PubMedCentral® Posted Date
2-13-2024
PubMedCentral® Full Text Version
Post-print
Abstract
Sickle cell disease is a condition that can involve numerous organ systems secondary to vascular occlusion. Herein, we present a case of a 21-year-old male with sickle cell disease requiring long-term hydroxyurea therapy. Upon migrating to the United States from Yemen, the patient developed a rapidly progressive, exquisitely painful ulcer on his right lower extremity. Given his country of origin, a broad differential, including select infectious diseases, was essential. Moreover, establishing the unequivocally correct diagnosis was crucial to determine proper and safe therapy. Ultimately, a lesional biopsy demonstrated numerous sickled red blood cells occluding blood vessels, leading to the diagnosis of sickle cell disease-related leg ulceration.
Keywords
derm path, non-malignant hematology, hydroxyurea use, non-healing ulcer, sickle cell disease complications
Published Open-Access
yes
Recommended Citation
Patel, Jay R; Montejano, Rubi; Hopkins, Christina; et al., "The Curious Case of a Painful Leg Ulcer" (2024). Faculty, Staff and Students Publications. 487.
https://digitalcommons.library.tmc.edu/baylor_docs/487