Publication Date

5-1-2022

Journal

Reviews in Cardiovascular Medicine

DOI

10.31083/j.rcm2305157

PMID

39077617

PMCID

PMC11273972

PubMedCentral® Posted Date

4-27-2022

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes

Keywords

troponin, high sensitivity troponin, chest pain, acute coronary syndrome, biomarkers

Abstract

This review focuses on the strengths and limitations of conventional and high-sensitivity troponin in the evaluation of patients with suspected acute coronary syndromes. High-sensitivity troponin (hsTn) assays represent a significant innovation over prior generation troponin assays. Owing to superior analytical precision, hsTn permits more rapid "rule-in" and "rule-out" of myocardial infarction. Furthermore, hsTn assays, in properly implemented clinical pathways, permit a reduction in the portion of patients requiring extended observation and testing.

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