Language

English

Publication Date

1-1-2025

Journal

Movement Disorders Clinical Practice

DOI

10.1002/mdc3.14272

PMID

39529252

PMCID

PMC11736892

PubMedCentral® Posted Date

11-11-2024

PubMedCentral® Full Text Version

Post-print

Abstract

Background: Deep Brain Stimulation (DBS) has been demonstrated to improve quality of life in patients with refractory dystonia and Tourette's syndrome (TS). Because of the young age at onset of these disorders, and the marked benefit from DBS, pregnancy in patients who have received DBS is becoming a more frequent clinical occurrence, although clear management guidelines are lacking.

Cases: We report 14 new pregnancies in patients with dystonia or TS and DBS.

Literature review: Upon review of the literature, 23 pregnancies in patients with dystonia or TS were previously reported in seven articles.

Conclusion: Based on the available data from a total of 37 pregnancies, DBS does not seem associated with worse pregnancy outcome. However, careful planning and communication between neurologist, anesthesiologist and obstetrician are key. A registry on pregnancy outcome in patients with DBS should be generated to facilitate the development of guidelines.

Keywords

Humans, Deep Brain Stimulation, Pregnancy, Female, Tourette Syndrome, Dystonia, Pregnancy Complications, Adult, Pregnancy Outcome, Young Adult, dystonia, Tourette, deep brain stimulation, pregnancy, C‐section

Published Open-Access

yes

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