Nonexposed Endoscopic Full Thickness Resection of Residual Disease After Definitive Chemoradiation for Locally Advanced Gastric Cancer

Authors

Brennan W Gioe
Bryan C Luu
Michael M Ittmann
George Chen
Yvonne H Sada
Wasseem Skef

Language

English

Publication Date

10-1-2025

DOI

10.14309/crj.0000000000001840

PMID

41041164

PMCID

PMC12487942

PubMedCentral® Posted Date

10-1-2025

PubMedCentral® Full Text Version

Post-print

Abstract

Salvage endoscopic resection of residual esophageal neoplasia for patients that prefer to avoid surgery or are poor surgical candidates has been reported. We report a case of gastric signet ring cell carcinoma with residual disease after definitive chemoradiotherapy, that was treated with nonexposed endoscopic full thickness resection. This endoscopic resection achieved negative margins, with postresection surveillance endoscopy and imaging showing no evidence of disease. This case highlights the potential use of salvage endoscopic resection as a therapy for residual gastric cancer after chemoradiation in patients where surgery is not an option.

Keywords

gastric cancer, signet ring cell, endoscopic resection

Published Open-Access

yes

Recommended Citation

Gioe, Brennan W; Luu, Bryan C; Ittmann, Michael M; et al., "Nonexposed Endoscopic Full Thickness Resection of Residual Disease After Definitive Chemoradiation for Locally Advanced Gastric Cancer" (2025). Faculty and Staff Publications. 5580.
https://digitalcommons.library.tmc.edu/baylor_docs/5580