Publication Date
7-1-2025
Journal
Children
DOI
10.3390/children11060709
PMID
38929288
PMCID
PMC11202264
PubMedCentral® Posted Date
6-8-2024
PubMedCentral® Full Text Version
Post-print
Abstract
Patients admitted to a pediatric intensive care unit (PICU) need individualized nutrition support that is tailored to their particular disease severity, nutritional status, and therapeutic interventions. We aim to evaluate how calories and proteins are provided during the first seven days of hospitalization for children in critical condition with organ dysfunction (OD). A single-center retrospective cohort study of children aged 2–18 years, mechanically ventilated > 48 h, and admitted > 7 days to a PICU from 2016 to 2017 was carried out. Nutrition support included enteral and parenteral nutrition. We calculated scores for the Pediatric Sequential Organ Failure Assessment (pSOFA) on days 1 and 3 of admission, with OD defined as a score > 5. Of 4199 patient admissions, 164 children were included. The prevalence of OD for days 1 and 3 was 79.3% and 78.7%, respectively. On day 3, when pSOFA scores trended upward, decreased, or remained unchanged, median (IQR) caloric intake was 0 (0–15), 9.2 (0–25), and 22 (1–43) kcal/kg/day, respectively (p = 0.0032); when pSOFA scores trended upward, decreased, or remained unchanged, protein intake was 0 (0–0.64), 0.44 (0–1.25), and 0.66 (0.04–1.67) g/kg/day, respectively (p = 0.0023). Organ dysfunction was prevalent through the first 72 h of a PICU stay. When the pSOFA scores trended downward or remained unchanged, caloric and protein intakes were higher than those that trended upward.
Keywords
Humans, Extracorporeal Membrane Oxygenation, Male, Female, Infant, Hemorrhage, Retrospective Studies, Child, Preschool, Child, Nervous System Diseases, Infant, Newborn, Severity of Illness Index, Treatment Outcome
Published Open-Access
yes
Recommended Citation
Doane, Katherine; Guffey, Danielle; Loftis, Laura L; et al., "Short-Term Neurologic Outcomes in Pediatric Extracorporeal Membrane Oxygenation Are Proportional to Bleeding Severity Graded by a Novel Bleeding Scale" (2025). Faculty and Staff Publications. 5741.
https://digitalcommons.library.tmc.edu/baylor_docs/5741