Language
English
Publication Date
1-1-2025
Journal
Pediatric Diabetes
DOI
10.1155/pedi/8425032
PMID
40612706
PMCID
PMC12226158
PubMedCentral® Posted Date
6-26-2025
PubMedCentral® Full Text Version
Post-print
Abstract
Hypertriglyceridemia (HTG) in the setting of newly diagnosed diabetes is common in both adult and pediatric populations, as insulin deficiency promotes lipolysis and impairs triglyceride (TG) clearance. Severe HTG (defined as TG levels above 1000 mg/dL) in pediatric patients with new-onset type 1 diabetes mellitus (T1D) is rare; the true incidence and sequela of this phenomenon have not been well characterized. We present a single-center experience on severe HTG in pediatric patients with new-onset T1D between 2013 and 2022 and summarize the cases previously reported in the literature. Our cases display variability in their presentation and in their association with high-risk complications, such as acute pancreatitis. We discuss suggestions of early screening for HTG and pancreatitis in patients with protracted abdominal pain, and close monitoring of those identified to have significant HTG.
Keywords
Humans, Hypertriglyceridemia, Diabetes Mellitus, Type 1, Child, Male, Female, Adolescent, Pancreatitis, Child, Preschool, hypertriglyceridemia, lipid, new-onset diabetes, pediatric
Published Open-Access
yes
Recommended Citation
Macke, Colleen A; Al-Gadi, Iman; Bansal, Nidhi; et al., "Hypertriglyceridemia in New-Onset Type 1 Pediatric Diabetes" (2025). Faculty and Staff Publications. 5783.
https://digitalcommons.library.tmc.edu/baylor_docs/5783