Envisioning Future Urinary Tract Infection Diagnostics

Authors

Robin Patel
Christopher R Polage
Jennifer Dien Bard
Larissa May
Francesca M Lee
Valeria Fabre
Mary K Hayden
Sarah D B Doernberg
David A Haake
Barbara W Trautner
Larissa Grigoryan
Ephraim L Tsalik
Kimberly E Hanson

Publication Date

4-9-2022

Journal

Clinical Infectious Diseases

DOI

10.1093/cid/ciab749

PMID

34463708

PMCID

PMC8994576

PubMedCentral® Posted Date

8-31-2021

PubMedCentral® Full Text Version

Post-Print

Published Open-Access

yes

Keywords

Anti-Bacterial Agents, Drug Resistance, Bacterial, Humans, United States, Urinary Tract Infections, urinary tract infection, UTI, laboratory diagnosis, diagnostics

Abstract

Urinary tract infections (UTIs) are among the most common bacterial infections in the United States and are a major driver of antibiotic use, both appropriate and inappropriate, across healthcare settings. Novel UTI diagnostics are a strategy that might enable better UTI treatment. Members of the Antibacterial Resistance Leadership Group Laboratory Center and the Infectious Diseases Society of America Diagnostics Committee convened to envision ideal future UTI diagnostics, with a view towards improving delivery of healthcare, patient outcomes and experiences, and antibiotic use, addressing which types of UTI diagnostics are needed and how companies might approach development of novel UTI diagnostics.