Language
English
Publication Date
8-1-2025
Journal
Journal of Pediatric Pharmacology and Therapeutics
DOI
10.5863/JPPT-24-00073
PMID
40821425
PMCID
PMC12351486
PubMedCentral® Posted Date
8-11-2025
PubMedCentral® Full Text Version
Post-print
Abstract
Drug induced neutropenia is an uncommon but potentially serious side effect in children receiving prolonged β-lactam antibiotic therapy. Management of β-lactam induced neutropenia in children remains challenging and often requires antibiotic therapy interruption or modification. There are limited data in pediatric patients about use of granulocyte-colony stimulating factor (G-CSF) for the treatment of drug induced neutropenia. We report the use of G-CSF for β-lactam induced neutropenia in four pediatric patients between the ages of 3 months and 18 years with bacterial meningitis in this case series.
Keywords
β-lactam, bacterial meningitis, granulocyte-colony stimulating factor, neutropenia
Published Open-Access
yes
Recommended Citation
Yen, Cheng Yu; Kaplan, Sheldon L; Palazzi, Debra L; et al., "Use of Granulocyte-Colony Stimulating Factor for Beta-Lactam Induced Neutropenia in Children With Bacterial Meningitis" (2025). Faculty, Staff and Students Publications. 5972.
https://digitalcommons.library.tmc.edu/baylor_docs/5972