Language
English
Publication Date
1-1-2024
Journal
Nature Materials
DOI
10.1038/s41563-023-01680-4
PMID
37814117
PMCID
PMC10972531
PubMedCentral® Posted Date
7-1-2024
PubMedCentral® Full Text Version
Author MSS
Abstract
Magnetoelectric materials convert magnetic fields into electric fields. These materials are often used in wireless electronic and biomedical applications. For example, magnetoelectrics could enable the remote stimulation of neural tissue, but the optimal resonance frequencies are typically too high to stimulate neural activity. Here we describe a self-rectifying magnetoelectric metamaterial for a precisely timed neural stimulation. This metamaterial relies on nonlinear charge transport across semiconductor layers that allow the material to generate a steady bias voltage in the presence of an alternating magnetic field. We generate arbitrary pulse sequences with time-averaged voltage biases in excess of 2 V. As a result, we can use magnetoelectric nonlinear metamaterials to wirelessly stimulate peripheral nerves to restore a sensory reflex in an anaesthetized rat model and restore signal propagation in a severed nerve with latencies of less than 5 ms. Overall, these results showing the rational design of magnetoelectric metamaterials support applications in advanced biotechnology and electronics.
Keywords
Rats, Animals, Magnetic Fields, Electronics
Published Open-Access
yes
Recommended Citation
Chen, Joshua C; Bhave, Gauri; Alrashdan, Fatima; et al., "Self-Rectifying Magnetoelectric Metamaterials for Remote Neural Stimulation and Motor Function Restoration" (2024). Faculty, Staff and Students Publications. 6202.
https://digitalcommons.library.tmc.edu/baylor_docs/6202