Language

English

Publication Date

1-1-2026

Journal

Open Forum Infectious Diseases

DOI

10.1093/ofid/ofaf784

PMID

41567261

PMCID

PMC12817971

PubMedCentral® Posted Date

1-20-2026

PubMedCentral® Full Text Version

Post-print

Abstract

Parasitic infections are often perceived as diseases of low-resource countries, yet they impose a significant and overlooked burden in the United States—especially among immigrants, low-income individuals, and other marginalized populations. This perspectives article examines the case of Mr. X, a landscaper in Houston diagnosed with neurocysticercosis, who faced unaffordable drug costs despite the availability of effective, off-patent treatments. Through his story, we explore the broader issue of pricing for commonly and not-so-commonly prescribed antiparasitic medications, highlighting the role of systemic market failures, regulatory hurdles, and restrictive assistance programs in limiting access to care. The consequences of incomplete treatment include long-term disability, public health risks, and deepened health disparities. We propose policy solutions, including reforms to the Orphan Drug Act, expansion of Medicare negotiation powers, and investment in public-interest drug production, to improve affordability and ensure equitable access to essential antiparasitic drugs.

Keywords

antiparasitic drugs, drug pricing, health disparities, medication access, neurocysticercosis, Orphan Drug Act

Published Open-Access

yes

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