Language

English

Publication Date

12-1-2025

Journal

JACC: Advances

DOI

10.1016/j.jacadv.2025.102330

PMID

41952649

PMCID

PMC12805173

PubMedCentral® Posted Date

12-17-2025

PubMedCentral® Full Text Version

Post-print

Abstract

With rising life expectancy, the population of older adults over the age of 65 is rapidly expanding, with women comprising the majority. Structural heart disease is common in this group, and transcatheter interventions have transformed its management. Optimal outcomes require careful consideration of sex-specific differences. This review examines transcatheter structural heart interventions in older adults with a focus on sex-based outcomes, procedural planning, and current knowledge gaps.

Keywords

aging, cardiovascular outcomes, frailty, sex differences, transcatheter structural heart interventions

Published Open-Access

yes

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Graphical Abstract

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