Language

English

Publication Date

1-1-2025

Journal

Data Science in Science

DOI

10.1080/26941899.2025.2474943

PMID

42394892

PMCID

PMC13327678

PubMedCentral® Posted Date

7-3-2026

PubMedCentral® Full Text Version

Author MSS

Abstract

We propose a Bayesian covariate-dependent anti-logistic circadian model for analyzing activity data collected via wrist-worn wearable devices. The proposed approach integrates covariates into the modeling of the amplitude and phase parameters, facilitating cohort-level analysis with enhanced flexibility and interpretability. To promote model sparsity, we employ an l1-ball projection prior, enabling precise control over complexity while identifying significant predictors. We assess performances on simulated data and then apply the method to real-world actigraphy data from people with epilepsy. Our results demonstrate the model’s effectiveness in uncovering complex relationships among demographic, psychological, and medical factors influencing rest-activity rhythms, offering insights for personalized clinical assessments and healthcare interventions.

Keywords

Anti-logistic Circadian model, rest-activity rhythms, l1-ball projection prior, multi-subject modeling, wereable devices

Published Open-Access

yes

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