Indomethacin-Induced Ductus Arteriosus Closure and Aortopulmonary Collateral Formation in Fetal Ebstein Anomaly with Circular Shunt

Authors

• Mounica Y Rao
• Ruth M Vaughan
• Shaine A Morris
• Nancy A Ayres
• Maggie J Nguyen
• Jianhong Zhang
• Betul Yilmaz Furtun

Language

English

Publication Date

11-1-2025

Journal

CASE

DOI

10.1016/j.case.2025.06.004

PMID

41623569

PMCID

PMC12859409

PubMedCentral® Posted Date

7-28-2025

PubMedCentral® Full Text Version

Post-print

Abstract

• Indomethacin may improve hemodynamics in fetal Ebstein anomaly with circular shunt. • Ductal closure with indomethacin can impair pulmonary blood flow and growth. • Ductal closure may result in subsequent development of APCs. • Irreversible ductal closure may affect postnatal surgical palliation. • Fetal echocardiography is vital for early intervention and medication titration.

Keywords

Fetal Ebstein anomaly, Circular shunt, Ductus arteriosus closure, Indomethacin, NSAID

Published Open-Access

yes

Recommended Citation

Rao, Mounica Y; Vaughan, Ruth M; Morris, Shaine A; et al., "Indomethacin-Induced Ductus Arteriosus Closure and Aortopulmonary Collateral Formation in Fetal Ebstein Anomaly with Circular Shunt" (2025). Faculty, Staff and Students Publications. 7498.
https://digitalcommons.library.tmc.edu/baylor_docs/7498