Language
English
Publication Date
7-2-2025
Journal
American Journal of Tropical Medicine and Hygiene
DOI
10.4269/ajtmh.24-0636
PMID
40262571
PMCID
PMC12225586
PubMedCentral® Posted Date
4-22-2025
PubMedCentral® Full Text Version
Post-print
Abstract
Relapsing fever caused by Borrelia sp. is a neglected disease in Mexico and more studies are needed to update its presence in multiple regions of the country. Here, recombinant proteins glycerophosphodiester phosphodiesterase (GlpQ) and three Borrelia immunogenic protein A (BipA) variants were used for serosurveillance in 142 human serum samples. Results showed that two persons were positive to Borrelia extracts and GlpQ but negative to all three BipA, suggesting they were infected by relapsing fever spirochetes of a yet to be determined species. This shows that testing for GlpQ and Borrelia extracts are a useful tool for potential infections and grants their use in other regions and studies in Mexico.
Keywords
Humans, Mexico, Relapsing Fever, Borrelia, Antibodies, Bacterial, Bacterial Proteins, Male, Phosphoric Diester Hydrolases, Adult, Antigens, Bacterial, Female
Published Open-Access
yes
Recommended Citation
Luna-Rojas, Sofía L; Vázquez-Guerrero, Edwin; Hernández-Martínez, Jose A; et al., "Serological Analysis Indicating the Exposure of Two Volunteers to Relapsing Fever Borrelia sp. in Nayarit, Mexico" (2025). Faculty, Staff and Students Publications. 7541.
https://digitalcommons.library.tmc.edu/baylor_docs/7541