Authors

    Language

    English

    Publication Date

    4-21-2026

    Journal

    Current Atherosclerosis Reports

    DOI

    10.1007/s11883-026-01409-z

    PMID

    42012759

    PMCID

    PMC13099778

    PubMedCentral® Posted Date

    4-21-2026

    PubMedCentral® Full Text Version

    Post-print

    Abstract

    Purpose of review

    Despite advances in type 1 diabetes (T1D) management, mortality is still increased, with cardiovascular disease (CVD) as the leading cause. Dyslipidemia is a highly prevalent modifiable CVD risk factor. We reviewed the existing literature on CVD mortality in T1D to highlight CVD risk in pediatric patients with T1D.

    Recent findings

    Pathophysiology of T1D and premature CVD risk is still not fully understood. Dyslipidemia remains a highly prevalent and undertreated CV risk factor in T1D. Statins have been shown to be safe and effective to improve CVD risk in adults with T1D, and in children with familial hypercholesterolemia, in addition to improving lipids levels in children with T1D.

    Summary

    T1D is associated with premature CVD mortality, and dyslipidemia is still a highly prevalent and undertreated CVD risk factor. We aim to educate and empower pediatric providers to optimize management of dyslipidemia in pediatric patients with T1D to potentially decrease the CVD risk.

    Keywords

    Humans, Diabetes Mellitus, Type 1, Dyslipidemias, Cardiovascular Diseases, Child, Heart Disease Risk Factors, Risk Factors, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Cardiovascular disease, Dyslipidemia, Pediatric, Type 1 diabetes

    Published Open-Access

    yes

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