Language

English

Publication Date

4-21-2026

Journal

Current Atherosclerosis Reports

DOI

10.1007/s11883-026-01409-z

PMID

42012759

PMCID

PMC13099778

PubMedCentral® Posted Date

4-21-2026

PubMedCentral® Full Text Version

Post-print

Abstract

Purpose of review

Despite advances in type 1 diabetes (T1D) management, mortality is still increased, with cardiovascular disease (CVD) as the leading cause. Dyslipidemia is a highly prevalent modifiable CVD risk factor. We reviewed the existing literature on CVD mortality in T1D to highlight CVD risk in pediatric patients with T1D.

Recent findings

Pathophysiology of T1D and premature CVD risk is still not fully understood. Dyslipidemia remains a highly prevalent and undertreated CV risk factor in T1D. Statins have been shown to be safe and effective to improve CVD risk in adults with T1D, and in children with familial hypercholesterolemia, in addition to improving lipids levels in children with T1D.

Summary

T1D is associated with premature CVD mortality, and dyslipidemia is still a highly prevalent and undertreated CVD risk factor. We aim to educate and empower pediatric providers to optimize management of dyslipidemia in pediatric patients with T1D to potentially decrease the CVD risk.

Keywords

Humans, Diabetes Mellitus, Type 1, Dyslipidemias, Cardiovascular Diseases, Child, Heart Disease Risk Factors, Risk Factors, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Cardiovascular disease, Dyslipidemia, Pediatric, Type 1 diabetes

Published Open-Access

yes

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