Language
English
Publication Date
12-1-2025
Journal
Journal of Child Psychology and Psychiatry
DOI
10.1111/jcpp.70010
PMID
40631408
PMCID
PMC12338068
Abstract
Background: Childhood mental health conditions commonly cooccur, with potential treatment implications. Autistic children frequently experience anxiety and attention deficit/hyperactivity disorder (ADHD). We investigated the implications of this cooccurrence for Cognitive Behavioural Therapy (CBT), a front-line treatment for anxiety in autistic children. We tested whether (1) ADHD predicts anxiety treatment response, (2) ADHD improves in response to anxiety treatment and (3) ADHD improvement is related to reductions in anxiety.
Method: Autistic children with elevated anxiety (N = 167) enrolled in a multisite, randomised controlled trial comparing standard CBT, autism-adapted CBT and treatment as usual. ADHD symptoms and severity were assessed via a parent-report questionnaire and clinical interview, respectively. Linear regressions (questions 1 and 2) and linear mixed models (question 3) were conducted with adjustments for multiple comparisons.
Results: Participants meeting diagnostic criteria for ADHD (62%) had greater pretreatment anxiety severity and anxiety-related functional impairment, particularly at school. ADHD did not moderate anxiety response following CBT. Receiving CBT (standard or adapted) predicted reduction in evaluator-rated ADHD severity, but not parent-reported symptoms. Reduction in anxiety severity predicted reduction in ADHD symptoms and severity.
Conclusions: Existing CBT programmes are suitable for treating anxiety in autistic children with cooccurring ADHD. Future research should identify mechanisms through which CBT for anxiety also mitigates ADHD, with the aim of improving treatment precision and effectiveness.
Keywords
Humans, Attention Deficit Disorder with Hyperactivity, Male, Child, Female, Cognitive Behavioral Therapy, Comorbidity, Anxiety Disorders, Adolescent, Outcome Assessment, Health Care, Autistic Disorder, Anxiety, Autism Spectrum Disorder, Autism, attention deficit/hyperactivity disorder, anxiety, cognitive behavioural therapy
Published Open-Access
yes
Recommended Citation
Ng-Cordell, Elise; Storch, Eric A; Kendall, Philip C; et al., "Implications of Cooccurring ADHD for the Cognitive Behavioural Treatment of Anxiety in Autistic Children" (2025). Faculty, Staff and Students Publications. 7925.
https://digitalcommons.library.tmc.edu/baylor_docs/7925