Publication Date
3-1-2024
Journal
(IUCr) IUCrJ - IUCr Journals - International Union of Crystallography
DOI
10.1107/S2052252524001246
PMID
38358351
PMCID
PMC10916293
PubMedCentral® Posted Date
2-15-2024
PubMedCentral® Full Text Version
Post-print
Published Open-Access
no
Keywords
Data Curation, Cryoelectron Microscopy, cryogenic-specimen electron microscopy, data archiving, validation, quality control, Electron Microscopy Data Bank, Protein Data Bank, single-particle cryoEM, databases, bioinformatics, structure determination
Abstract
In January 2020, a workshop was held at EMBL-EBI (Hinxton, UK) to discuss data requirements for the deposition and validation of cryoEM structures, with a focus on single-particle analysis. The meeting was attended by 47 experts in data processing, model building and refinement, validation, and archiving of such structures. This report describes the workshop's motivation and history, the topics discussed, and the resulting consensus recommendations. Some challenges for future methods-development efforts in this area are also highlighted, as is the implementation to date of some of the recommendations.
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Biomedical Informatics Commons, Medical Microbiology Commons, Medical Specialties Commons