Language
English
Publication Date
6-1-2021
Journal
Thoroax
DOI
10.1136/thoraxjnl-2020-216244
PMID
33483364
PMCID
PMC8238310
PubMedCentral® Posted Date
6-1-2022
PubMedCentral® Full Text Version
Post-print
Abstract
Screening for pulmonary fibrosis may help to identify early stages of the disease. We assessed the psychological impact of screening undiagnosed first-degree relatives of patients with pulmonary fibrosis by administering two validated measures after participants received their results: the Decisional Regret Scale and the Feelings About genomiC Testing Results Questionnaire. More than 90% of relatives reported either no or mild decisional regret. Increased measures of decisional regret and negative feelings were present in those found to have a low diffusion capacity of carbon monoxide or interstitial lung abnormalities. Results of telomere length and genetic testing did not significantly impact regret.
Keywords
Aged, Female, Follow-Up Studies, Genetic Testing, Humans, Male, Mass Screening, Middle Aged, Pedigree, Pulmonary Fibrosis, Retrospective Studies, Surveys and Questionnaires, Time Factors, pulmonary fibrosis, MUC5B, decisional regret, genetic counseling, telomere length
Published Open-Access
yes
Recommended Citation
Carmichael, Nikkola; Martinez Manzano, Jose M; Quesada-Arias, Luisa D; et al., "Psychological impact of genetic and clinical screening for pulmonary fibrosis on asymptomatic first-degree relatives of affected individuals" (2021). Faculty and Staff Publications. 814.
https://digitalcommons.library.tmc.edu/baylor_docs/814
Included in
Biochemistry, Biophysics, and Structural Biology Commons, Biology Commons, Medical Sciences Commons, Medical Specialties Commons