Publication Date
1-11-2021
Journal
Baylor University Medical Center Proceedings
DOI
10.1080/08998280.2020.1866943
PMID
33953465
PMCID
PMC8059917
PubMedCentral® Posted Date
1-11-2021
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Keywords
Intravascular lymphoma, rapidly progressive dementia
Abstract
Intravascular lymphoma is an uncommon subtype of B-cell lymphoma with neoplastic cells limited to the lumen of small blood vessels. We report a case of a 52-year-old man who presented with constitutional symptoms and rapidly progressive dementia. He was found to have diffuse leptomeningeal and faint parenchymal enhancement on magnetic resonance imaging and was subsequently diagnosed with intravascular lymphoma following a brain biopsy. He responded remarkably well to systemic and intrathecal chemotherapy. The diagnosis and treatment of intravascular lymphoma have been guided by a few case reports and are largely based on expert opinion.
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