Publication Date
2-1-2024
Journal
Reviews in Cardiovascular Medicine
DOI
10.31083/j.rcm2502066
PMID
39077332
PMCID
PMC11263144
PubMedCentral® Posted Date
2-18-2024
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Keywords
left main coronary artery disease, percutaneous coronary intervention, coronary artery bypass grafting, revascularization
Abstract
Significant left main coronary artery disease is a very high-risk subgroup of coronary artery disease that is a crucial indicator of heightened morbidity and mortality rates. Despite its clinical significance, uncertainties persist regarding the optimal management strategy for patients, particularly given its phenotypic variations. Existing evidence-based guidelines offer insights into revascularization options, yet questions remain regarding long-term prognoses and clinical outcomes when comparing percutaneous coronary intervention to coronary artery bypass grafting. This comprehensive review aims to provide an in-depth analysis of contemporary strategies for the diagnosis, assessment, and treatment of left main coronary artery disease. By synthesizing current literature and addressing the evolving landscape of revascularization modalities, this review seeks to contribute valuable insights for clinicians and researchers grappling with the complexities of managing left main coronary artery disease.
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Biochemistry, Biophysics, and Structural Biology Commons, Cardiology Commons, Cardiovascular Diseases Commons, Medical Sciences Commons