Dietary Effects on Monocyte Phenotypes in Subjects With Hypertriglyceridemia and Metabolic Syndrome

Authors

Zeqin Lian
Xiao-Yuan Dai Perrard
Antu Kalathookunnel Antony
Xueying Peng
Lu Xu
Jing Ni
Bingqian Zhang
Veronica O'Brien
Anum Saeed
Xiaoming Jia
Aliza Hussain
Bing Yu
Scott I Simon
Frank M Sacks
Ron C Hoogeveen
Christie M Ballantyne
Huaizhu Wu

Publication Date

5-1-2023

Journal

Basic to Translational Science - JACC

DOI

10.1016/j.jacbts.2023.02.011

PMID

37325398

PMCID

PMC10264566

PubMedCentral® Posted Date

4-26-2023

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes

Keywords

ASCVD, high saturated fat diet, hypertriglyceridemia, low saturated fat diet, monocyte

Abstract

In patients with hypertriglyceridemia, a short-term low–saturated fat vs high–saturated fat diet induced lower plasma lipids and improved monocyte phenotypes. These findings highlight the role of diet fat content and composition for monocyte phenotypes and possibly cardiovascular disease risk in these patients. (Effects of Dietary Interventions on Monocytes in Metabolic Syndrome; NCT03591588)

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