Ultraviolet Inactivation of Wild-Type Adenovirus Isolates
Abstract
Current drinking water guidelines set by the EPA for ultraviolet (UV) disinfection recommend 186mJ/cm2 for a 4-log reduction against waterborne viral pathogens. Some viruses such as human adenovirus (HAdV) show extreme resistance to UV inactivation. Published literature suggest human adenoviruses require 232mJ/cm2 of UV-C for a 4-log reduction. HAdV requires close to 4 times more UV dosage in comparison to less-resistant waterborne pathogens. The inactivation dosage of these highly resistant viruses may pose as better guideline standards for UV inactivation requirements for drinking water sources. The purpose of this project is to determine the UV-C fluence needed for a 4-log reduction in wild-type adenovirus isolates recovered from the environment. The inactivation rates for these viruses are also important for the development of more efficient UV systems.
Subject Area
Microbiology|Public health
Recommended Citation
Navar, Cesar A, "Ultraviolet Inactivation of Wild-Type Adenovirus Isolates" (2017). Texas Medical Center Dissertations (via ProQuest). AAI10617942.
https://digitalcommons.library.tmc.edu/dissertations/AAI10617942