Language
English
Publication Date
1-1-2026
Journal
Dystonia
DOI
10.3389/dyst.2026.15082
PMID
42592533
PMCID
PMC13465952
PubMedCentral® Posted Date
8-13-2026
PubMedCentral® Full Text Version
Author MSS
Abstract
Dystonia is a complex neurological disorder characterized by sustained or intermittent abnormal movements and/or postures. However, dystonia's non-motor symptoms, particularly the sleep disturbances, are critical yet underexplored concerns that affect all ages. Here, we synthesize current knowledge on the motor and non-motor domains of dystonia, emphasizing the functional interconnections and plasticity within cerebellar motor, cognitive, and sleep-associated circuits to motivate more comprehensive and effective treatments that improve overall quality of life.
Keywords
cerebellum, cognition, dystonia, movement, neuromodulation, neuroplasticity, sleep
Published Open-Access
yes
Recommended Citation
Linda H Kim, Cheryl Brandenburg, and Roy V Sillitoe, "Cerebellar Motor and Non-Motor Contributions to Dystonia Pathophysiology and Treatment" (2026). Duncan NRI Faculty and Staff Publications. 251.
https://digitalcommons.library.tmc.edu/duncar_nri_pub/251
Included in
Genetic Phenomena Commons, Medical Genetics Commons, Neurology Commons, Neurosciences Commons